Mitochondrial Calcium Uptake 1 (MICU1) (Middle Region) Peptide
MICU1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5512913
Aperçu rapide pour Mitochondrial Calcium Uptake 1 (MICU1) (Middle Region) Peptide (ABIN5512913)
Antigène
MICU1
(Mitochondrial Calcium Uptake 1 (MICU1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- GMRHRDRPTT GNTLKSGLCS ALTTYFFGAD LKGKLTIKNF LEFQRKLQHD
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CBARA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
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Sujet
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This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: CALC, EFHA3, MPXPS, CBARA1
Protein Size: 278 -
ID gène
- 10367
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NCBI Accession
- NM_001195518, NP_001182447
Antigène
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